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Carbamazepine 10,11-epoxide

CAS No. 36507-30-9

Carbamazepine 10,11-epoxide ( —— )

产品货号. M28116 CAS No. 36507-30-9

Carbamazepine 10,11-epoxide is an active metabolite of the anticonvulsant carbamazepine.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥316 有现货
10MG ¥518 有现货
25MG ¥1037 有现货
50MG ¥1555 有现货
100MG ¥2325 有现货
200MG ¥3491 有现货
500MG ¥5775 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Carbamazepine 10,11-epoxide
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Carbamazepine 10,11-epoxide is an active metabolite of the anticonvulsant carbamazepine.
  • 产品描述
    Carbamazepine 10,11-epoxide is an active metabolite of the anticonvulsant carbamazepine.It is formed from carbamazepine by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2C8 in microsomes prepared from HepG2 cells expressing CYP3A4 or CYP2C8, respectively.Carbamazepine 10,11-epoxide has anticonvulsant activity against maximal electroshock-induced seizures in mice.2It has been found in wastewater effluent.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    PDE4;PDE4B1;PDE4D7
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    36507-30-9
  • 分子量
    252.3
  • 分子式
    C15H12N2O2
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    NC(=O)N1c2ccccc2C2OC2c2ccccc12
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Zheng-Qiang Zou, et al. Novel Phosphodiesterase 4 Inhibitor FCPR03 Alleviates Lipopolysaccharide-Induced Neuroinflammation by Regulation of the cAMP/PKA/CREB Signaling Pathway and NF- κ B Inhibition. J Pharmacol Exp Ther. 2017 Jul;362(1):67-77.
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