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Carbamazepine 10,11-epoxide
CAS No. 36507-30-9
Carbamazepine 10,11-epoxide ( —— )
产品货号. M28116 CAS No. 36507-30-9
卡马西平 10,11-环氧化物是抗惊厥药卡马西平的活性代谢物。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥316 | 有现货 |
|
| 10MG | ￥518 | 有现货 |
|
| 25MG | ￥1037 | 有现货 |
|
| 50MG | ￥1555 | 有现货 |
|
| 100MG | ￥2325 | 有现货 |
|
| 200MG | ￥3491 | 有现货 |
|
| 500MG | ￥5775 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Carbamazepine 10,11-epoxide
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述卡马西平 10,11-环氧化物是抗惊厥药卡马西平的活性代谢物。
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产品描述Carbamazepine 10,11-epoxide is an active metabolite of the anticonvulsant carbamazepine.It is formed from carbamazepine by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2C8 in microsomes prepared from HepG2 cells expressing CYP3A4 or CYP2C8, respectively.Carbamazepine 10,11-epoxide has anticonvulsant activity against maximal electroshock-induced seizures in mice.2It has been found in wastewater effluent.
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体外实验——
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体PDE4|PDE4B1|PDE4D7
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研究领域——
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适应症——
化学信息
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CAS Number36507-30-9
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分子量252.273
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分子式C15H12N2O2
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 125 mg/mL (495.50 mM)
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SMILESNC(=O)N1c2ccccc2C2OC2c2ccccc12
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Zheng-Qiang Zou, et al. Novel Phosphodiesterase 4 Inhibitor FCPR03 Alleviates Lipopolysaccharide-Induced Neuroinflammation by Regulation of the cAMP/PKA/CREB Signaling Pathway and NF- κ B Inhibition. J Pharmacol Exp Ther. 2017 Jul;362(1):67-77.
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